It’s all about context. There are options that are context and age appropriate that aren’t condescending or clinically reductive.
Men’s bathroom and Women’s bathroom > male bathroom and female bathroom
“Hey, guys/gents”, “hey, girls/ladies” > “hey, men”, “hey, women”
First woman President > first female President > first girl President
This is your annual reminder that Santa’s steeds as classically depicted are all Ladies. Male Caribou shed their antlers before Christmas. That’s right! The sleigh runs on girl power! Red One even paid homage to this fun fact this year.